Identification and characterization of receptor-specific peptides for siRNA delivery

Tumor-targeted delivery of siRNA remains a major barrier in fully realizing the therapeutic potential of RNA interference. While cell-penetrating peptides (CPP) are promising siRNA carrier candidates, they are universal internalizers that lack cell-type specificity. Herein, we design and screen a li...

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Podrobná bibliografie
Hlavní autoři: Ren, Yin, Hauert, Sabine, Lo, Justin H., Bhatia, Sangeeta N
Další autoři: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Médium: Článek
Jazyk:en_US
Vydáno: American Chemical Society (ACS) 2012
On-line přístup:http://hdl.handle.net/1721.1/75316
https://orcid.org/0000-0001-5981-2589
https://orcid.org/0000-0002-1293-2097