Lineage-based identification of cellular states and expression programs

Lineage-based identification of cellular states and expression programs

We present a method, LineageProgram, that uses the developmental lineage relationship of observed gene expression measurements to improve the learning of developmentally relevant cellular states and expression programs. We find that incorporating lineage information allows us to significantly improv...

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Bibliographic Details
Main Authors: Hashimoto, Tatsunori Benjamin, Jaakkola, Tommi S., Sherwood, Richard, Mazzoni, Esteban O., Wichterle, Hynek, Gifford, David K.
Other Authors: Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Format: Article
Language:en_US
Published: Oxford University Press 2012
Online Access:http://hdl.handle.net/1721.1/75412
https://orcid.org/0000-0003-0521-5855
https://orcid.org/0000-0002-2199-0379
https://orcid.org/0000-0003-1709-4034

Internet

http://hdl.handle.net/1721.1/75412
https://orcid.org/0000-0003-0521-5855
https://orcid.org/0000-0002-2199-0379
https://orcid.org/0000-0003-1709-4034

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