Lineage-based identification of cellular states and expression programs
We present a method, LineageProgram, that uses the developmental lineage relationship of observed gene expression measurements to improve the learning of developmentally relevant cellular states and expression programs. We find that incorporating lineage information allows us to significantly improv...
Main Authors: | Hashimoto, Tatsunori Benjamin, Jaakkola, Tommi S., Sherwood, Richard, Mazzoni, Esteban O., Wichterle, Hynek, Gifford, David K. |
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Other Authors: | Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science |
Format: | Article |
Language: | en_US |
Published: |
Oxford University Press
2012
|
Online Access: | http://hdl.handle.net/1721.1/75412 https://orcid.org/0000-0003-0521-5855 https://orcid.org/0000-0002-2199-0379 https://orcid.org/0000-0003-1709-4034 |
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