Enhancing synaptogenesis in diseases characterized by deficiencies in brain synapses

The loss of hippocampal and cortical synapses, resulting from impaired synaptogenesis, accelerated synaptic degeneration, or both, is one of the earliest neuropathologic findings in Alzheimer’s Disease and is the finding that best correlates with cognitive symptoms (DeKosky and Scheff, 1990; Terry e...

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Bibliographic Details
Main Author: Wurtman, Richard Jay
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:en_US
Published: Frontiers Research Foundation 2012
Online Access:http://hdl.handle.net/1721.1/75768
https://orcid.org/0000-0001-8286-6825