Removing human immunodeficiency virus (HIV) from human blood using immobilized heparin

Heparin covalently attached to a water-insoluble resin suspended in HIV-infected aqueous buffer or whole blood captures the virus; subsequent physical separation of the immobilized heparin reduced the viral titers by over 80 and 50%, respectively. The detoxification concept has been validated by bot...

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Bibliographic Details
Main Authors: Nassar, Roger A., Browne, Edward P., Chen, Jianzhu, Klibanov, Alexander M.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Springer-Verlag 2013
Online Access:http://hdl.handle.net/1721.1/76226
https://orcid.org/0000-0003-3830-714X
https://orcid.org/0000-0002-5687-6154