Safe and Efficient Tetrazole Synthesis in a Continuous Flow Microreactor
Safer flow: The synthesis of 5-substituted tetrazoles in flow (see scheme) is safe, efficient, scalable, requires no metal promoter, and uses a near-equimolar amount of NaN[subscript 3], yet nonetheless displays a broad substrate scope. The hazards associated with HN[subscript 3] are essentially eli...
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Format: | Article |
Language: | en_US |
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Wiley Blackwell
2013
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Online Access: | http://hdl.handle.net/1721.1/76267 https://orcid.org/0000-0002-8601-7799 |