Safe and Efficient Tetrazole Synthesis in a Continuous Flow Microreactor

Safer flow: The synthesis of 5-substituted tetrazoles in flow (see scheme) is safe, efficient, scalable, requires no metal promoter, and uses a near-equimolar amount of NaN[subscript 3], yet nonetheless displays a broad substrate scope. The hazards associated with HN[subscript 3] are essentially eli...

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Detalhes bibliográficos
Principais autores: Palde, Prakash B., Jamison, Timothy F.
Outros Autores: Massachusetts Institute of Technology. Department of Chemistry
Formato: Artigo
Idioma:en_US
Publicado em: Wiley Blackwell 2013
Acesso em linha:http://hdl.handle.net/1721.1/76267
https://orcid.org/0000-0002-8601-7799