Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis
Most tumors exhibit increased glucose metabolism to lactate, however, the extent to which glucose-derived metabolic fluxes are used for alternative processes is poorly understood [1, 2]. Using a metabolomics approach with isotope labeling, we found that in some cancer cells a relatively large amount...
Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
Nature Publishing Group
2013
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Online Access: | http://hdl.handle.net/1721.1/76302 https://orcid.org/0000-0002-6702-4192 https://orcid.org/0000-0003-0046-1360 https://orcid.org/0000-0001-6909-4568 |