Design of lipid nanoparticle delivery agents for multivalent display of recombinant Env trimers in HIV vaccination

Background: Immunization strategies that elicit antibodies capable of neutralizing diverse strains of the virus will likely be an important part of a successful vaccine against HIV. The envelope trimer is the only neutralizing target on the virus, and strategies to promote durable, high avidity ant...

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Detalhes bibliográficos
Principais autores: Pejawar Gaddy, Sharmila, Kovacs, J., Barouch, D., Chen, B., Irvine, Darrell J.
Outros Autores: Massachusetts Institute of Technology. Department of Materials Science and Engineering
Formato: Artigo
Idioma:en_US
Publicado em: BioMed Central Ltd. 2013
Acesso em linha:http://hdl.handle.net/1721.1/76620