The eradication of bacterial persisters with antibiotic-generated hydroxyl radical

During Mycobacterium tuberculosis infection, a population of bacteria likely becomes refractory to antibiotic killing in the absence of genotypic resistance, making treatment challenging. We describe an in vitro model capable of yielding a phenotypically antibiotic-tolerant subpopulation of cells, o...

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Detalhes bibliográficos
Principais autores: Haseley, Nathan Scott, Grant, Sarah Schmidt, Kaufmann, Benjamin B., Chand, Nikhilesh S., Hung, Deborah T.
Outros Autores: Harvard University--MIT Division of Health Sciences and Technology
Formato: Artigo
Idioma:en_US
Publicado em: National Academy of Sciences (U.S.) 2013
Acesso em linha:http://hdl.handle.net/1721.1/76727
https://orcid.org/0000-0003-2616-4030