Disclosing pathogenic genetic variants to research participants: Quantifying an emerging ethical responsibility
There is an emerging consensus that when investigators obtain genomic data from research participants, they may incur an ethical responsibility to inform at-risk individuals about clinically significant variants discovered during the course of their research. With whole-exome sequencing becoming com...
Main Authors: | Cassa, Christopher A., Savage, Sarah K., Taylor, Patrick L., Green, Robert C., McGuire, Amy L., Mandl, Kenneth D. |
---|---|
Other Authors: | Harvard University--MIT Division of Health Sciences and Technology |
Format: | Article |
Language: | en_US |
Published: |
Cold Spring Harbor Laboratory Press
2013
|
Online Access: | http://hdl.handle.net/1721.1/76767 |
Similar Items
-
Large Numbers of Genetic Variants Considered to be Pathogenic are Common in Asymptomatic Individuals
by: Cassa, Christopher A., et al.
Published: (2014) -
Non-pharmaceutical interventions and the emergence of pathogen variants
by: Ashby, B, et al.
Published: (2022) -
Need to disclose disability
by: Mohd Noor, Alisha Nur
Published: (2019) -
Carbon emission: motivation to disclose
by: Wan Ahmad, Wan Norhayati, et al.
Published: (2018) -
Predictable and precise template-free CRISPR editing of pathogenic variants
by: Shen, Max Walt, et al.
Published: (2020)