Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins

Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins

Selective translation of survival proteins is an important facet of the cellular stress response. We recently demonstrated that this translational control involves a stress-specific reprogramming of modified ribonucleosides in tRNA. Here we report the discovery of a step-wise translational control m...

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Bibliographic Details
Main Authors: Chan, Tsz Yan Clement, Pang, Yan Ling Joy, Deng, Wenjun, Indrakanti, Ramesh Babu, Dyavaiah, Madhu, Begley, Thomas J., Dedon, Peter C.
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences
Format: Article
Language:en_US
Published: Nature Publishing Group 2013
Online Access:http://hdl.handle.net/1721.1/76775
https://orcid.org/0000-0003-0011-3067
https://orcid.org/0000-0001-8533-2706
https://orcid.org/0000-0001-7940-3459

Internet

http://hdl.handle.net/1721.1/76775
https://orcid.org/0000-0003-0011-3067
https://orcid.org/0000-0001-8533-2706
https://orcid.org/0000-0001-7940-3459

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