Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins
Selective translation of survival proteins is an important facet of the cellular stress response. We recently demonstrated that this translational control involves a stress-specific reprogramming of modified ribonucleosides in tRNA. Here we report the discovery of a step-wise translational control m...
Main Authors: | Chan, Tsz Yan Clement, Pang, Yan Ling Joy, Deng, Wenjun, Indrakanti, Ramesh Babu, Dyavaiah, Madhu, Begley, Thomas J., Dedon, Peter C. |
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Other Authors: | Massachusetts Institute of Technology. Center for Environmental Health Sciences |
Format: | Article |
Language: | en_US |
Published: |
Nature Publishing Group
2013
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Online Access: | http://hdl.handle.net/1721.1/76775 https://orcid.org/0000-0003-0011-3067 https://orcid.org/0000-0001-8533-2706 https://orcid.org/0000-0001-7940-3459 |
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