Barcoding bias in high-throughput multiplex sequencing of miRNA
Second-generation sequencing is gradually becoming the method of choice for miRNA detection and expression profiling. Given the relatively small number of miRNAs and improvements in DNA sequencing technology, studying miRNA expression profiles of multiple samples in a single flow cell lane becomes f...
Main Authors: | , , , , , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
Cold Spring Harbor Laboratory Press
2013
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Online Access: | http://hdl.handle.net/1721.1/76787 |