Barcoding bias in high-throughput multiplex sequencing of miRNA

Barcoding bias in high-throughput multiplex sequencing of miRNA

Second-generation sequencing is gradually becoming the method of choice for miRNA detection and expression profiling. Given the relatively small number of miRNAs and improvements in DNA sequencing technology, studying miRNA expression profiles of multiple samples in a single flow cell lane becomes f...

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Bibliographic Details
Main Authors: Alon, Shahar, Vigneault, Francois, Eminaga, Seda, Christodoulou, Danos C., Seidman, Jonathan G., Church, George M., Eisenberg, Eli
Other Authors: Ragon Institute of MGH, MIT and Harvard
Format: Article
Language:en_US
Published: Cold Spring Harbor Laboratory Press 2013
Online Access:http://hdl.handle.net/1721.1/76787

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