Conserved features of intermediates in amyloid assembly determine their benign or toxic states
Some amyloid-forming polypeptides are associated with devastating human diseases and others provide important biological functions. For both, oligomeric intermediates appear during amyloid assembly. Currently we have few tools for characterizing these conformationally labile intermediates and discer...
| Main Authors: | , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
National Academy of Sciences
2013
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| Online Access: | http://hdl.handle.net/1721.1/77145 https://orcid.org/0000-0003-1307-882X |