Non Linear Programming (NLP) Formulation for Quantitative Modeling of Protein Signal Transduction Pathways
Modeling of signal transduction pathways plays a major role in understanding cells' function and predicting cellular response. Mathematical formalisms based on a logic formalism are relatively simple but can describe how signals propagate from one protein to the next and have led to the constru...
Main Authors: | Mitsos, Alexander, Melas, Ioannis N., Morris, Melody Kay, Saez-Rodriguez, Julio, Lauffenburger, Douglas A., Alexopoulos, Leonidas G. |
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Other Authors: | Massachusetts Institute of Technology. Cell Decision Process Center |
Format: | Article |
Language: | en_US |
Published: |
Public Library of Science
2013
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Online Access: | http://hdl.handle.net/1721.1/77202 |
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