Engineering of In Vitro 3D Capillary Beds by Self-Directed Angiogenic Sprouting

In recent years, microfluidic systems have been used to study fundamental aspects of angiogenesis through the patterning of single-layered, linear or geometric vascular channels. In vivo, however, capillaries exist in complex, three-dimensional (3D) networks, and angiogenic sprouting occurs with a d...

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Bibliographic Details
Main Authors: Chan, Juliana Maria, Zervantonakis, Ioannis K., Rimchala, Tharathorn, Polacheck, William Joseph, Whisler, Jordan, Kamm, Roger Dale
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Public Library of Science 2013
Online Access:http://hdl.handle.net/1721.1/77208
https://orcid.org/0000-0002-3299-9424
https://orcid.org/0000-0003-2728-0746
https://orcid.org/0000-0002-7232-304X