Sequence-dependent sliding kinetics of p53

Sequence-dependent sliding kinetics of p53

Proper timing of gene expression requires that transcription factors (TFs) efficiently locate and bind their target sites within a genome. Theoretical studies have long proposed that one-dimensional sliding along DNA while simultaneously reading its sequence can accelerate TF’s location of target si...

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Bibliographic Details
Main Authors: Leith, Jason S., Tafvizi, Anahita, Huang, Fang, Uspal, William Eric, Fersht, Alan R., Oijen, Antoine M. van, Doyle, Patrick S, Mirny, Leonid A
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2013
Online Access:http://hdl.handle.net/1721.1/77237
https://orcid.org/0000-0002-0785-5410

Internet

http://hdl.handle.net/1721.1/77237
https://orcid.org/0000-0002-0785-5410

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