Pathological crystallization of human immunoglobulins

Pathological crystallization of human immunoglobulins

Condensation of Igs has been observed in pharmaceutical formulations and in vivo in cases of cryoglobulinemia. We report a study of monoclonal IgG cryoglobulins overexpressed by two patients with multiple myeloma. These cryoglobulins form crystals, and we measured their solubility lines. Depending o...

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Bibliographic Details
Main Authors: Wang, Ying, Lomakin, Aleksey, Hideshima, Teru, Laubach, Jacob P., Ogun, Olutayo, Richardson, Paul G., Munshi, Nikhil C., Anderson, Kenneth C., Benedek, George B.
Other Authors: MIT Materials Research Laboratory
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2013
Online Access:http://hdl.handle.net/1721.1/77567
https://orcid.org/0000-0003-2414-524X
https://orcid.org/0000-0001-6684-7608

Internet

http://hdl.handle.net/1721.1/77567
https://orcid.org/0000-0003-2414-524X
https://orcid.org/0000-0001-6684-7608

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