Synthetic incoherent feedforward circuits show adaptation to the amount of their genetic template

Natural and synthetic biological networks must function reliably in the face of fluctuating stoichiometry of their molecular components. These fluctuations are caused in part by changes in relative expression efficiency and the DNA template amount of the network-coding genes. Gene product levels cou...

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Bibliographic Details
Main Authors: Bleris, Leonidas, Xie, Zhen, Glass, David, Adadey, Asa, Sontag, Eduardo, Benenson, Yaakov
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Nature Publishing Group 2013
Online Access:http://hdl.handle.net/1721.1/77595