Extensive alternative polyadenylation during zebrafish development

The post-transcriptional fate of messenger RNAs (mRNAs) is largely dictated by their 3′ untranslated regions (3′ UTRs), which are defined by cleavage and polyadenylation (CPA) of pre-mRNAs. We used poly(A)-position profiling by sequencing (3P-seq) to map poly(A) sites at eight developmental stages a...

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Bibliographic Details
Main Authors: Ulitsky, Igor, Shkumatava, Alena, Jan, Calvin H., Subtelny, Alexander Orest, Koppstein, David Neal Pira, Bell, George W., Sive, Hazel L., Bartel, David
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Cold Spring Harbor Laboratory Press 2013
Online Access:http://hdl.handle.net/1721.1/77596
https://orcid.org/0000-0002-3872-2856
https://orcid.org/0000-0002-4890-424X
https://orcid.org/0000-0001-5029-5909