Confinement to Organelle-Associated Inclusion Structures Mediates Asymmetric Inheritance of Aggregated Protein in Budding Yeast

Confinement to Organelle-Associated Inclusion Structures Mediates Asymmetric Inheritance of Aggregated Protein in Budding Yeast

The division of the S. cerevisiae budding yeast, which produces one mother cell and one daughter cell, is asymmetric with respect to aging. Remarkably, the asymmetry of yeast aging coincides with asymmetric inheritance of damaged and aggregated proteins by the mother cell. Here, we show that misfold...

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Bibliographic Details
Main Authors: Spokoini, Rachel, Moldavski, Ofer, Nahmias, Yaakov, England, Jeremy L., Schuldiner, Maya, Kaganovich, Daniel
Other Authors: Massachusetts Institute of Technology. Department of Physics
Format: Article
Language:en_US
Published: Elsevier 2013
Online Access:http://hdl.handle.net/1721.1/77894
https://orcid.org/0000-0001-8414-3153

Internet

http://hdl.handle.net/1721.1/77894
https://orcid.org/0000-0001-8414-3153

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