Confinement to Organelle-Associated Inclusion Structures Mediates Asymmetric Inheritance of Aggregated Protein in Budding Yeast
The division of the S. cerevisiae budding yeast, which produces one mother cell and one daughter cell, is asymmetric with respect to aging. Remarkably, the asymmetry of yeast aging coincides with asymmetric inheritance of damaged and aggregated proteins by the mother cell. Here, we show that misfold...
Main Authors: | Spokoini, Rachel, Moldavski, Ofer, Nahmias, Yaakov, England, Jeremy L., Schuldiner, Maya, Kaganovich, Daniel |
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Other Authors: | Massachusetts Institute of Technology. Department of Physics |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2013
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Online Access: | http://hdl.handle.net/1721.1/77894 https://orcid.org/0000-0001-8414-3153 |
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