Effects of thymic selection of the T cell repertoire on HLA-class I associated control of HIV infection

Effects of thymic selection of the T cell repertoire on HLA-class I associated control of HIV infection

Without therapy, most people infected with human immunodeficiency virus (HIV) ultimately progress to AIDS. Rare individuals (‘elite controllers’) maintain very low levels of HIV RNA without therapy, thereby making disease progression and transmission unlikely. Certain HLA class I alleles are markedl...

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Bibliographic Details
Main Authors: Kosmrlj, Andrej, Read, Elizabeth L., Qi, Ying, Allen, Todd M., Altfeld, Marcus, Deeks, Steven G., Pereyra, Florencia, Carrington, Mary, Walker, Bruce D., Chakraborty, Arup K
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: Nature Publishing Group 2013
Online Access:http://hdl.handle.net/1721.1/77959
https://orcid.org/0000-0003-1268-9602

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http://hdl.handle.net/1721.1/77959
https://orcid.org/0000-0003-1268-9602

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