Modularity and hormone sensitivity of the Drosophila melanogaster insulin receptor/target of rapamycin interaction proteome

Modularity and hormone sensitivity of the Drosophila melanogaster insulin receptor/target of rapamycin interaction proteome

Genetic analysis in Drosophila melanogaster has been widely used to identify a system of genes that control cell growth in response to insulin and nutrients. Many of these genes encode components of the insulin receptor/target of rapamycin (InR/TOR) pathway. However, the biochemical context of this...

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Bibliographic Details
Main Authors: Jevtov, Irena, Glatter, Timo, Schittenhelm, Ralf B., Rinner, Oliver, Roguska, Katarzyna, Wepf, Alexander, Junger, Martin A., Kohler, Katja, Choi, Hyungwon, Schmidt, Alexander, Nesvizhskii, Alexey I., Stocker, Hugo, Hafen, Ernst, Aebersold, Ruedi, Gstaiger, Matthias
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Nature Publishing Group 2013
Online Access:http://hdl.handle.net/1721.1/77992

Internet

http://hdl.handle.net/1721.1/77992

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