Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors

Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors

The presence of growth-induced solid stresses in tumors has been suspected for some time, but these stresses were largely estimated using mathematical models. Solid stresses can deform the surrounding tissues and compress intratumoral lymphatic and blood vessels. Compression of lymphatic vessels ele...

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Bibliographic Details
Main Authors: Martin, John Daniel, Jain, Saloni R., Stylianopoulosa, Triantafyllos, Chauhana, Vikash P., Bardeesy, Nabeel, Diop-Frimpong, Benjamin, Stylianopoulos, Triantafyllos, Smith, Barbara L., Ferrone, Cristina R., Hornicek, Francis J., Boucher, Yves, Munn, Lance L., Jain, Rakesh K.
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2013
Online Access:http://hdl.handle.net/1721.1/78002

Internet

http://hdl.handle.net/1721.1/78002

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