SOX2 Co-Occupies Distal Enhancer Elements with Distinct POU Factors in ESCs and NPCs to Specify Cell State
SOX2 is a master regulator of both pluripotent embryonic stem cells (ESCs) and multipotent neural progenitor cells (NPCs); however, we currently lack a detailed understanding of how SOX2 controls these distinct stem cell populations. Here we show by genome-wide analysis that, while SOX2 bound to a d...
Main Authors: | , , , , , , , |
---|---|
Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
Public Library of Science
2013
|
Online Access: | http://hdl.handle.net/1721.1/78345 https://orcid.org/0000-0002-5239-9557 https://orcid.org/0000-0002-2902-7288 https://orcid.org/0000-0003-1381-4313 https://orcid.org/0000-0001-9249-8181 https://orcid.org/0000-0003-3491-4962 |