Linking Proteomic and Transcriptional Data through the Interactome and Epigenome Reveals a Map of Oncogene-induced Signaling

Linking Proteomic and Transcriptional Data through the Interactome and Epigenome Reveals a Map of Oncogene-induced Signaling

Cellular signal transduction generally involves cascades of post-translational protein modifications that rapidly catalyze changes in protein-DNA interactions and gene expression. High-throughput measurements are improving our ability to study each of these stages individually, but do not capture th...

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Bibliographic Details
Main Authors: Huang, Shao-shan Carol, Clarke, David C., Gosline, Sara Jane Calafell, Labadorf, Adam, Chouinard, Candace R., Gordon, William, Lauffenburger, Douglas A., Fraenkel, Ernest
Other Authors: Massachusetts Institute of Technology. Cell Decision Process Center
Format: Article
Language:en_US
Published: Public Library of Science 2013
Online Access:http://hdl.handle.net/1721.1/78612
https://orcid.org/0000-0001-9249-8181
https://orcid.org/0000-0002-6534-4774

Internet

http://hdl.handle.net/1721.1/78612
https://orcid.org/0000-0001-9249-8181
https://orcid.org/0000-0002-6534-4774

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