Linking Proteomic and Transcriptional Data through the Interactome and Epigenome Reveals a Map of Oncogene-induced Signaling
Cellular signal transduction generally involves cascades of post-translational protein modifications that rapidly catalyze changes in protein-DNA interactions and gene expression. High-throughput measurements are improving our ability to study each of these stages individually, but do not capture th...
Main Authors: | Huang, Shao-shan Carol, Clarke, David C., Gosline, Sara Jane Calafell, Labadorf, Adam, Chouinard, Candace R., Gordon, William, Lauffenburger, Douglas A., Fraenkel, Ernest |
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Other Authors: | Massachusetts Institute of Technology. Cell Decision Process Center |
Format: | Article |
Language: | en_US |
Published: |
Public Library of Science
2013
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Online Access: | http://hdl.handle.net/1721.1/78612 https://orcid.org/0000-0001-9249-8181 https://orcid.org/0000-0002-6534-4774 |
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