High-resolution genetic mapping with pooled sequencing

Background: Modern genetics has been transformed by high-throughput sequencing. New experimental designs in model organisms involve analyzing many individuals, pooled and sequenced in groups for increased efficiency. However, the uncertainty from pooling and the challenge of noisy sequencing data de...

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Bibliographic Details
Main Authors: Edwards, Matthew Douglas, Gifford, David K.
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:English
Published: BioMed Central Ltd 2013
Online Access:http://hdl.handle.net/1721.1/78673
https://orcid.org/0000-0002-5845-748X
https://orcid.org/0000-0003-1709-4034