High-resolution genetic mapping with pooled sequencing
Background: Modern genetics has been transformed by high-throughput sequencing. New experimental designs in model organisms involve analyzing many individuals, pooled and sequenced in groups for increased efficiency. However, the uncertainty from pooling and the challenge of noisy sequencing data de...
Main Authors: | Edwards, Matthew Douglas, Gifford, David K. |
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Other Authors: | Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory |
Format: | Article |
Language: | English |
Published: |
BioMed Central Ltd
2013
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Online Access: | http://hdl.handle.net/1721.1/78673 https://orcid.org/0000-0002-5845-748X https://orcid.org/0000-0003-1709-4034 |
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