Effects of dopamine depletion on LFP oscillations in striatum are task- and learning-dependent and selectively reversed by l-DOPA

Effects of dopamine depletion on LFP oscillations in striatum are task- and learning-dependent and selectively reversed by l-DOPA

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A major physiologic sign in Parkinson disease is the occurrence of abnormal oscillations in cortico-basal ganglia circuits, which can be normalized by l-DOPA therapy. Under normal circumstances, oscillatory activity in these circuits is modulated as behaviors are learned and performed, but how dopam...

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Bibliographic Details
Main Authors: Lemaire, Nune, Ledia, F. Hernandez, Hu, Dan, Kubota, Yasuo, Howe, Mark William, Graybiel, Ann M.
Other Authors: McGovern Institute for Brain Research at MIT
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2013
Online Access:http://hdl.handle.net/1721.1/78873
https://orcid.org/0000-0001-9197-7711
https://orcid.org/0000-0003-2381-0834
https://orcid.org/0000-0002-4326-7720

Internet

http://hdl.handle.net/1721.1/78873
https://orcid.org/0000-0001-9197-7711
https://orcid.org/0000-0003-2381-0834
https://orcid.org/0000-0002-4326-7720

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