Effects of dopamine depletion on LFP oscillations in striatum are task- and learning-dependent and selectively reversed by l-DOPA
A major physiologic sign in Parkinson disease is the occurrence of abnormal oscillations in cortico-basal ganglia circuits, which can be normalized by l-DOPA therapy. Under normal circumstances, oscillatory activity in these circuits is modulated as behaviors are learned and performed, but how dopam...
Main Authors: | Lemaire, Nune, Ledia, F. Hernandez, Hu, Dan, Kubota, Yasuo, Howe, Mark William, Graybiel, Ann M. |
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Other Authors: | McGovern Institute for Brain Research at MIT |
Format: | Article |
Language: | en_US |
Published: |
National Academy of Sciences (U.S.)
2013
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Online Access: | http://hdl.handle.net/1721.1/78873 https://orcid.org/0000-0001-9197-7711 https://orcid.org/0000-0003-2381-0834 https://orcid.org/0000-0002-4326-7720 |
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