Self-Assembled Gold Nanoparticle Molecular Probes for Detecting Proteolytic Activity

Target-activatable fluorogenic probes based on gold nanoparticles (AuNPs) functionalized with self-assembled heterogeneous monolayers of dye-labeled peptides and poly(ethylene glycol) have been developed to visualize proteolytic activity in vivo. A one-step synthesis strategy that allows simple gene...

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Bibliographic Details
Main Authors: Mu, C. Jenny, LaVan, David A., Langer, Robert, Zetter, Bruce R.
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: American Chemical Society 2013
Online Access:http://hdl.handle.net/1721.1/79074
https://orcid.org/0000-0003-4255-0492