Engineering of Targeted Nanoparticles for Cancer Therapy Using Internalizing Aptamers Isolated by Cell-Uptake Selection

Engineering of Targeted Nanoparticles for Cancer Therapy Using Internalizing Aptamers Isolated by Cell-Uptake Selection

One of the major challenges in the development of targeted nanoparticles (NPs) for cancer therapy is to discover targeting ligands that allow for differential binding and uptake by the target cancer cells. Using prostate cancer (PCa) as a model disease, we developed a cell-uptake selection strategy...

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Bibliographic Details
Main Authors: Xiao, Zeyu, Levy-Nissenbaum, Etgar, Alexis, Frank, Luptak, Andrej, Teply, Benjamin A., Chan, Juliana Maria, Shi, Jinjun, Digga, Elise, Cheng, Judy, Langer, Robert, Farokhzad, Omid C.
Other Authors: MIT-Harvard Center for Cancer Nanotechnology Excellence
Format: Article
Language:en_US
Published: American Chemical Society 2013
Online Access:http://hdl.handle.net/1721.1/79109
https://orcid.org/0000-0001-6518-0311
https://orcid.org/0000-0002-2640-3006
https://orcid.org/0000-0003-4255-0492

Internet

http://hdl.handle.net/1721.1/79109
https://orcid.org/0000-0001-6518-0311
https://orcid.org/0000-0002-2640-3006
https://orcid.org/0000-0003-4255-0492

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