Engineering of Targeted Nanoparticles for Cancer Therapy Using Internalizing Aptamers Isolated by Cell-Uptake Selection
One of the major challenges in the development of targeted nanoparticles (NPs) for cancer therapy is to discover targeting ligands that allow for differential binding and uptake by the target cancer cells. Using prostate cancer (PCa) as a model disease, we developed a cell-uptake selection strategy...
Main Authors: | Xiao, Zeyu, Levy-Nissenbaum, Etgar, Alexis, Frank, Luptak, Andrej, Teply, Benjamin A., Chan, Juliana Maria, Shi, Jinjun, Digga, Elise, Cheng, Judy, Langer, Robert, Farokhzad, Omid C. |
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Other Authors: | MIT-Harvard Center for Cancer Nanotechnology Excellence |
Format: | Article |
Language: | en_US |
Published: |
American Chemical Society
2013
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Online Access: | http://hdl.handle.net/1721.1/79109 https://orcid.org/0000-0001-6518-0311 https://orcid.org/0000-0002-2640-3006 https://orcid.org/0000-0003-4255-0492 |
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