Intracellular Delivery of siRNA by Polycationic Superparamagnetic Nanoparticles

Intracellular Delivery of siRNA by Polycationic Superparamagnetic Nanoparticles

The siRNA transfection efficiency of nanoparticles (NPs), composed of a superparamagnetic iron oxide core modified with polycationic polymers (poly(hexamethylene biguanide) or branched polyethyleneimine), were studied in CHO-K1 and HeLa cell lines. Both NPs demonstrated to be good siRNA transfection...

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Bibliographic Details
Main Authors: Castillo, Betzaida, Badillo, Valerie, Hatton, T. Alan, Barletta, Gabriel, Bromberg, Lev E., Lopez, Xaira, Gonzalez Feliciano, Jose A., Gonzalez, Carlos I.
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:English
Published: Hindawi Publishing Corporation 2013
Online Access:http://hdl.handle.net/1721.1/79115
https://orcid.org/0000-0002-4558-245X

Internet

http://hdl.handle.net/1721.1/79115
https://orcid.org/0000-0002-4558-245X

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