Morphine Epigenomically Regulates Behavior through Alterations in Histone H3 Lysine 9 Dimethylation in the Nucleus Accumbens

Dysregulation of histone modifying enzymes has been associated with numerous psychiatric disorders. Alterations in G9a (Ehmt2), a histone methyltransferase that catalyzes the euchromatic dimethylation of histone H3 at lysine 9 (H3K9me2), has been implicated recently in mediating neural and behaviora...

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Bibliographic Details
Main Authors: Sun, Hao Sheng, Maze, Ian, Dietz, David M., Scobie, Kimberly N., Kennedy, Pamela J., Damez-Werno, Diane, Neve, Rachael L., Zachario, Venetia, Shen, Li, Nestler, Eric J.
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:en_US
Published: Society for Neuroscience 2013
Online Access:http://hdl.handle.net/1721.1/79352
https://orcid.org/0000-0002-3854-5968