On-Chip Activation and Subsequent Detection of Individual Antigen-Specific T Cells

On-Chip Activation and Subsequent Detection of Individual Antigen-Specific T Cells

The frequencies of antigen-specific CD4+ T cells in samples of human tissue have been difficult to determine accurately ex vivo, particularly for autoimmune diseases such as multiple sclerosis or type 1 diabetes. Conventional approaches involve the expansion of primary T cells in vitro to increase t...

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Bibliographic Details
Main Authors: Song, Qing, Han, Qing, Bradshaw, Elizabeth M., Kent, Sally C., Raddassi, Khadir, Nilsson, Bjorn, Nepom, Gerald T., Hafler, David A., Love, J. Christopher
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:en_US
Published: American Chemical Society 2013
Online Access:http://hdl.handle.net/1721.1/79369
https://orcid.org/0000-0002-7989-2376

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http://hdl.handle.net/1721.1/79369
https://orcid.org/0000-0002-7989-2376

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