Nano-Layered Microneedles for Transcutaneous Delivery of Polymer Nanoparticles and Plasmid DNA

Multilayer-coated microneedles achieve transcutaneous delivery of plasmid DNA to the viable epidermis. Cy3-labeled plasmid DNA encoding luciferase (yellow) is deposited on biodegradable microneedle arrays through multilayer self-assembly and then delivered to the skin by microneedle application to a...

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Bibliographic Details
Main Authors: DeMuth, Peter Charles, Su, Xingfang, Samuel, Raymond E., Hammond, Paula T, Irvine, Darrell J
Other Authors: Massachusetts Institute of Technology. Institute for Soldier Nanotechnologies
Format: Article
Language:en_US
Published: Wiley-Blackwell Publishers 2013
Online Access:http://hdl.handle.net/1721.1/79375