Production and characterization of carbamazepine nanocrystals by electrospraying for continuous pharmaceutical manufacturing

In this paper, an electrospray technique followed by annealing at high temperatures was developed to produce nanocrystals of carbamazepine (CBZ), a poorly water-soluble drug, for continuous pharmaceutical manufacturing process. Electrospraying solutions of CBZ in methanol obeys the expected scaling...

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Bibliographic Details
Main Authors: Wang, Mao, Rutledge, Gregory C., Myerson, Allan S., Trout, Bernhardt L.
Other Authors: Novartis-MIT Center for Continuous Manufacturing
Format: Article
Language:en_US
Published: Wiley Blackwell 2013
Online Access:http://hdl.handle.net/1721.1/79583
https://orcid.org/0000-0003-1417-9470
https://orcid.org/0000-0001-8137-1732