Identification of CDCP1 as a hypoxia-inducible factor 2  (HIF-2 ) target gene that is associated with survival in clear cell renal cell carcinoma patients

Identification of CDCP1 as a hypoxia-inducible factor 2  (HIF-2 ) target gene that is associated with survival in clear cell renal cell carcinoma patients

CUB domain-containing protein 1 (CDCP1) is a transmembrane protein that is highly expressed in stem cells and frequently overexpressed and tyrosine-phosphorylated in cancer. CDCP1 promotes cancer cell metastasis. However, the mechanisms that regulate CDCP1 are not well-defined. Here we show that hyp...

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Bibliographic Details
Main Authors: Emerling, B. M., Benes, Cyril H., Poulogiannis, G., Courtney, K., Liu, H., Choo-Wing, R., Bellinger, Gary, Tsukazawa, K. S., Brown, V., Signoretti, S., Soltoff, S. P., Cantley, Lewis C., Bell, Eric L.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2013
Online Access:http://hdl.handle.net/1721.1/80378

Internet

http://hdl.handle.net/1721.1/80378

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