Impact of deleterious passenger mutations on cancer progression
Cancer progression is driven by the accumulation of a small number of genetic alterations. However, these few driver alterations reside in a cancer genome alongside tens of thousands of additional mutations termed passengers. Passengers are widely believed to have no role in cancer, yet many passeng...
Main Authors: | , , , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
National Academy of Sciences (U.S.)
2013
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Online Access: | http://hdl.handle.net/1721.1/80381 https://orcid.org/0000-0002-0785-5410 |