BMP7 Gene Transfer via Gold Nanoparticles into Stroma Inhibits Corneal Fibrosis In Vivo

This study examined the effects of BMP7 gene transfer on corneal wound healing and fibrosis inhibition in vivo using a rabbit model. Corneal haze in rabbits was produced with the excimer laser performing -9 diopters photorefractive keratectomy. BMP7 gene was introduced into rabbit keratocytes by pol...

Full description

Bibliographic Details
Main Authors: Tandon, Ashish, Sharma, Ajay, Rodier, Jason T., Klibanov, Alexander M., Rieger, Frank G., Mohan, Rajiv R.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Public Library of Science 2013
Online Access:http://hdl.handle.net/1721.1/80696
https://orcid.org/0000-0003-3830-714X