Physical limits on cellular directional mechanosensing

Many eukaryotic cells are able to perform directional mechanosensing by directly measuring minute spatial differences in the mechanical stress on their membranes. Here, we explore the limits of a single mechanosensitive channel activation using a two-state double-well model for the gating mechanism....

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Bibliographic Details
Main Authors: Bouffanais, Roland, Sun, Jianmin, Yue, Dick K. P.
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering
Format: Article
Language:en_US
Published: American Physical Society 2013
Online Access:http://hdl.handle.net/1721.1/80755
https://orcid.org/0000-0002-0141-2168
https://orcid.org/0000-0003-1273-9964