Specific Trans-Synaptic Interaction with Inhibitory Interneuronal Neurexin Underlies Differential Ability of Neuroligins to Induce Functional Inhibitory Synapses

Specific Trans-Synaptic Interaction with Inhibitory Interneuronal Neurexin Underlies Differential Ability of Neuroligins to Induce Functional Inhibitory Synapses

Synaptic transmission depends on the matching and alignment of presynaptically released transmitters and postsynaptic neurotransmitter receptors. Neuroligin (NL) and Neurexin (Nrxn) proteins are trans-synaptic adhesion molecules that are important in validation and maturation of specific synapses. N...

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Bibliographic Details
Main Authors: Futai, Kensuke, Doty, Christopher D., Baek, Brian, Ryu, Jubin, Sheng, Morgan Hwa-Tze
Other Authors: Picower Institute for Learning and Memory
Format: Article
Language:en_US
Published: Society for Neuroscience 2013
Online Access:http://hdl.handle.net/1721.1/80785

Internet

http://hdl.handle.net/1721.1/80785

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