Constitutive nuclear lamina-genome interactions are highly conserved and associated with A/T-rich sequence

Constitutive nuclear lamina-genome interactions are highly conserved and associated with A/T-rich sequence

In metazoans, the nuclear lamina is thought to play an important role in the spatial organization of interphase chromosomes, by providing anchoring sites for large genomic segments named lamina-associated domains (LADs). Some of these LADs are cell-type specific, while many others appear constitutiv...

Full description

Bibliographic Details
Main Authors: Meuleman, Wouter, Peric-Hupkes, Daan, Kind, Jop, Beaudry, Jean-Bernard, Pagie, Ludo, Kellis, Manolis, Reinders, Marcel, Wessels, Lodewyk, van Steensel, Bas
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: Cold Spring Harbor Laboratory Press 2013
Online Access:http://hdl.handle.net/1721.1/80789
https://orcid.org/0000-0002-1196-5401

Internet

http://hdl.handle.net/1721.1/80789
https://orcid.org/0000-0002-1196-5401

Similar Items