Constitutive nuclear lamina-genome interactions are highly conserved and associated with A/T-rich sequence
In metazoans, the nuclear lamina is thought to play an important role in the spatial organization of interphase chromosomes, by providing anchoring sites for large genomic segments named lamina-associated domains (LADs). Some of these LADs are cell-type specific, while many others appear constitutiv...
Main Authors: | Meuleman, Wouter, Peric-Hupkes, Daan, Kind, Jop, Beaudry, Jean-Bernard, Pagie, Ludo, Kellis, Manolis, Reinders, Marcel, Wessels, Lodewyk, van Steensel, Bas |
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Other Authors: | Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory |
Format: | Article |
Language: | en_US |
Published: |
Cold Spring Harbor Laboratory Press
2013
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Online Access: | http://hdl.handle.net/1721.1/80789 https://orcid.org/0000-0002-1196-5401 |
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