Transnuclear Mice with Pre-defined T Cell Receptor Specificities Against Toxoplasma gondii Obtained via SCNT

Mice that are transgenic for rearranged antigen-specific T cell receptors (TCRs) are essential tools to study T cell development and function. Such TCRs are usually isolated from the relevant T cells after long-term culture, often after repeated antigen stimulation, which unavoidably skews the T cel...

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Bibliographic Details
Main Authors: Suh, Heikyung, Jaenisch, Rudolf, Ploegh, Hidde, Kirak, Oktay, Frickel, Eva-Maria, Grotenbreg, Gijsbert M.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: American Association for the Advancement of Science (AAAS) 2013
Online Access:http://hdl.handle.net/1721.1/81211
https://orcid.org/0000-0003-0787-298X
https://orcid.org/0000-0002-1090-6071