Stochastic Cytokine Expression Induces Mixed T Helper Cell States

During eukaryotic development, the induction of a lineage-specific transcription factor typically drives differentiation of multipotent progenitor cells, while repressing that of alternative lineages. This process is often mediated by some extracellular signaling molecules, such as cytokines that ca...

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Bibliographic Details
Main Authors: Fang, Miaoqing, Xie, Huangming, Dougan, Stephanie K., Ploegh, Hidde, van Oudenaarden, Alexander
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Public Library of Science 2013
Online Access:http://hdl.handle.net/1721.1/81213
https://orcid.org/0000-0002-1090-6071